Researchers at the University of Rochester have discovered a method, which could lead to people being able to grow back several rows of teeth much like sharks. There is a gene researchers say that prevents people and most mammals from forming additional teeth. To combat this researchers bred mice lacking this gene, the mice gained backup teeth next to their molars much like sharks and other non-mammals have. Dr Songtao Shi of the University of Southern California School of Dentistry was quoted as saying “It’s exciting. We have a clue what to do,” in relation to the University of Rochersters discovery.
Issues such as gum disease resulting in tooth loss are a major problem and current treatment is insufficient. If scientist are able to discover what triggers new tooth growth they believe they may be able to switch that early-in-life process on again in adulthood so that people may be able to regrow missing teeth.
The breeding of these mice, although a great achievement in the quest towards the regrowth of teeth, has its setbacks. Mice bred without the gene called Osr2, had cleft pallets severe enough to kill. Scientists believe though that a better understanding of this gene will lead to being able to prevent this defect and come closer to the aim of regenerative teeth in humans.
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Link: http://www.nydailynews.com/news/us_world/2009/02/26/2009-02-26_new_genetic_discovery_may_help_people_to.html
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